1. Take a closer look at the microscopic structure of the organ:
- lymph node is a bean-shaped organ surrounded by a connective tissue capsule that sends short supportive trabeculae into the node;
- lymph node can be divided into an outer part—the cortex, and an inner part—the medulla;
- in the cortex identify the following structures:
- connective tissue capsule and trabeculae,
- secondary lymphoid nodules each consisting of an outer corona (darker) and a germinal center, also called a reaction center,
- internodular lymphoid tissue,
- cortical lymphatic sinuses (the subcapsular sinus lying immediately below the capsule and a follicle, the intermediate sinus lying next to a trabecula);
- in the medulla, observe an anastomosing network of medullary cords (B-dependent areas) and medullary sinuses;
- the stroma is made up of reticular connective tissue and blood vessels;
- there is the paracortical region or the deep cortex (T-dependent zone) between the cortex and the medulla.
2. Draw and sign:
- I - cortex (1 – capsule, 2 – trabeculae, 3 – secondary lymphoid nodule with a germinal center, 4 – corona, 5 - subcapsular sinus, 6 - intermediate sinus, 7 – paracortex);
- II - medulla (8 - medullary cords, 9 – medullary sinus, 10 – reticular tissue).
3. Define and write significant features of the slide.